![]() ![]() This is a sign of an opioid overdose, which is a medical emergency. Pinpoint pupils are pupils that do not respond to changes in lighting. Opioids, including oxycodone, heroin, and fentanyl, are commonly misused drugs that have the opposite effect, causing pupils to constrict (miosis). Commonly misused drugs that dilate the pupils include: They’re the most commonly prescribed treatment for depression.ĭilated pupils are sometimes a sign of drug misuse. SSRIs enhance the effects of serotonin in the brain. Selective serotonin reuptake inhibitors (SSRIs)ĭepression, anxiety, post-traumatic stress disorder (PTSD) Both Ritalin and Adderall cause pupils to dilate. Stimulants, such as Ritalin and Adderall, are common in the treatment of attention-deficit hyperactivity disorder (ADHD). Sometimes called eye dilation drops, they’re commonly used during eye exams and surgeries.Īttention-deficit hyperactivity disorder (ADHD) Mydriatics are a class of drugs that cause pupil dilation. Parkinson’s disease and other movement disordersĭopamine precursors, such as Levodopa, help to increase synthesis of the neurotransmitter dopamine. Benadryl is a common OTC antihistamine.īenzodiazepines enhance the effects of a neurotransmitter called GABA, which relaxes the muscles.ĭecongestants shrink the blood vessels in the nose, helping to treat swelling, inflammation, and mucus buildup. Tricyclic antidepressants (TCAs) affect serotonin and norepinephrine, two chemical messengers that influence an extensive range of bodily functions.Īntihistamines block the action of histamine, an immune system chemical that triggers allergy symptoms, such as itchiness, a runny nose, and swelling. ![]() They include barbiturates like phenobarbital. MedicationĬhronic obstructive pulmonary disorder (COPD), nausea, motion sickness, overactive bladder (OAB), urinary incontinence (UI)Īnticholinergics block the action of the acetylcholine, a neurotransmitter involved in muscle contractions.Īntiepileptics work by impacting neurotransmitter activity or nerve impulses in the brain. As a result, taking some of these medications can cause pupil dilation as a side effect. Neurotransmitters play a role in pupil size. Many of the medications listed in the following table interfere with your brain’s chemical messengers, also known as neurotransmitters. Here are some prescription, over-the-counter, and commonly misused drugs that cause pupils to dilate. What drugs cause pupils to dilateĭrugs can affect the muscles that shrink or expand the pupils. Whether it’s caused by external or internalįactors, pupil dilation is an involuntary nervous system response. health conditions, such as Holmes-Adie syndrome, congenital aniridia, and mydriasis.You might have heard that looking at someone Such as color and distance, also affect pupil dilation. ThisĪllows more light to reach the retina, making it easier to see. What causes the pupils in our eyes to dilate? Read on to find out which prescription, over-the-counter, and commonly misused drugs affect pupil size. Other factors, such as drugs, can also affect pupil size. Pupils can grow or shrink according to different lighting conditions. The dark part of your eye is called the pupil.
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